A gene delivery system for the human heart
Engineering Design Projects (ES 100), the capstone course at the Harvard John A. Paulson School of Engineering and Applied Sciences, challenges seniors to engineer a creative solution to a real-world problem. Saron Meressi's project focused on optimizing cardiac gene delivery using adeno-associated virus (AAV) technology. She specifically designed a tunable, ventricle-specific gene delivery system that enables more precise targeting within the heart.